About Dad

Foundational medical history β€” the pre-existing conditions that reframe how to read the current regimen. Not new diagnoses. Long-standing context the care team is managing around.

Vitals

  • Name: Paul Mederos Sr.
  • DOB: 2/14/1963 Β· 63 years old
  • Pronouns: he/him
  • Lives: Apollo Beach, FL Β· with Angela (spouse)
  • Children: Paul (son) Β· Joe (son)

Major conditions

Tourette's syndrome

~50 years Β· since adolescence Β· biggest current complaint (5/27)

The original reason benzodiazepines entered Dad's life decades ago β€” alprazolam (Xanax) for tic and anxiety control. Tics are not a new symptom; they're a lifelong feature.

Current regimen targets the tics with NAC 300 mg + clonidine PRN, but Dad reports (5/27 call) the tics are his worst-felt symptom right now and a key motivator for moving to Phase 2. He's asked for a neurologist consult β€” Dr. Ignatov reportedly has done what he can.

AFib + Watchman implant

Watchman placed ~2025 (date TBC)

Atrial fibrillation triggered the mini-stroke (likely ischemic, AFib-related). Watchman (left atrial appendage closure device) was implanted to prevent further stroke without chronic anticoagulation. This is the reason for the current aspirin + clopidogrel DAPT β€” standard post-Watchman 45-day–6-month protocol, then step-down to aspirin alone.

Coronary artery disease + CABG

Quadruple bypass Β· November 2023

Established coronary artery disease + quadruple bypass in Nov 2023 (~2.5 years ago). Drives the high-intensity statin (atorvastatin 40 mg), the beta-blocker (metoprolol), and aggressive lipid management. Origin point for daily aspirin tolerance β€” taken without issue from this event onward.

Mini-stroke

TIA / small infarct Β· 2025

Discovered weeks after the event via subtle memory issues + slurred speech, triggered scans. Likely AFib-related embolic. Led to Watchman implant. Type TBC β€” needs cardio records.

Severe insulin resistance + atherogenic dyslipidemia

2025 Function Health baseline

Fasting insulin 57, A1c 5.8%, LDL-P 1789, small dense pattern B, HDL 26, TG 237. Already on the edge. Olanzapine 10 mg HS is the main pharma vector for worsening this. Full labs β†’

Chronic back pain

Original opioid indication

The 6-month oxycodone + morphine stretch was for back pain. Current non-opioid management: lidocaine patch nightly + acetaminophen PRN. Ibuprofen on PRN list but bleed risk on DAPT β€” should be flagged.

Sustained high-titer ANA

2025 baseline Β· β‰₯1:1280

Two draws positive at top of ladder, all specific autoantibodies negative, ESR + complement normal. Could be drug-induced (long benzo history). Not actionable on its own β€” historical context if any autoimmune-looking signs appear.

Allergies

Shellfish / seafood β€” highest-stakes

Severe childhood anaphylaxis that triggered cardiac arrest (likely Kounis syndrome β€” allergic coronary vasospasm from massive histamine release in cardiac tissue). Phase 3 care team must know.

Aspirin

Historical childhood allergy of unclear origin. Has been on daily low-dose aspirin since the Nov 2023 CABG with no problems. Currently tolerating. Chart should reflect "historical allergy, currently tolerated."

Epinephrine β€” reported but not actual

As a child, he had an anaphylactic reaction to shellfish, was given an EpiPen, then went into cardiac arrest. Most likely cause: the anaphylaxis itself triggered Kounis syndrome β€” the EpiPen catecholamine surge added cardiac strain on top of an already-stressed system. The anaphylaxis caused the arrest, not an epi reaction. In a future anaphylaxis emergency, epi is still indicated β€” administer in an ER with cardiac monitoring given his post-MI / AFib / Watchman status. Preference to avoid epi in non-emergency contexts is honored.

The recovery arc β€” what brought us here

  • ~30 years of daily Xanax (alprazolam) β€” originally prescribed for Tourette's tic and anxiety control as a teen, continued indefinitely.
  • ~6 months of opioids (oxycodone + morphine) β€” for chronic back pain.
  • April 9, 2026 β€” cold-turkey stop of both. This is the kindling event. CNS is now sensitized; any future abrupt withdrawal carries escalating seizure / death risk.
  • April 25, 2026 β€” ER admission Β· April 28 β€” discharged to Haven Detox.
  • Late April / early May β€” Baker Act, hold at NeuroBehavioral Hospital after reported SI.
  • May 13, 2026 β€” voluntary re-entry to Haven Detox.
  • Full timeline β†’